Lab resources
Various group resources (more coming).
The DNAscent software allows the detection of base analogues, such as BrdU, in nanopore sequence data.
DNAscent tools includes a set of scripts to process files produced by DNAscent, including converting output to modBAM format.
We have curated custom tracks for visualisation of our data at the UCSC genome browser. We aim to increase the number of datasets available via these links, please contact us if there is a particular dataset that you are interested in.
Scripts associated with using digital PCR to precisely and rapidly measure DNA copy number as a proxy for replication time.
We are developing virtual and self-guided training for base modification detection in ONT data.
OriDB provides a catalogue of confirmed and predicted DNA replication origin sites. At present this is limited to budding yeast (S. cerevisiae) and fission yeast (S. pombe).